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Neurofibroma: Causes, Symptoms, and Management

Posted on August 6, 2025

A neurofibroma is a benign tumor that develops from the nerve sheath, made up of Schwann cells, fibroblasts, and connective tissue. These growths can appear anywhere in the body but are often found in the skin or along deeper nerves.

Neurofibromas may occur as a single growth or as part of neurofibromatosis type 1 (NF1), a genetic disorder caused by NF1 gene mutations. While small neurofibromas are usually painless, larger or deeper ones can cause discomfort, numbness, or weakness if they compress nearby nerves.

Diagnosis involves physical examination, imaging tests like MRI or CT scans, and sometimes biopsy.

Treatment isn’t always required unless symptoms develop, in which case surgical removal may be recommended. Regular monitoring is essential to detect changes early, as rare cases can become malignant.

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